Mariana Castells, M.D., Ph.D. is a clinician-scientist with over 30 years of experience in allergy and immunology and over 200 publications. She is the Director of the Brigham and Women’s Hospital Mastocytosis Center, one of the few nationally and internationally recognized centers of excellence, which provides diagnosis, management, and treatment options for patients with mastocytosis and mast cell activation disorders. She is actively involved in mast cell-related research and is the PI on several clinical trials, including Blueprint Medicines, Cogent Biosciences, and Telios Pharmaceuticals. She is also the Director of the Drug Hypersensitivity and Desensitization Center at Brigham and Women’s Hospital and Dana Farber Cancer Institute. This center has provided over 900 high-risk desensitizations per year for over 30 years to patients with cancer and chronic inflammatory diseases. Dr. Castells is also a Professor of Medicine at Harvard Medical School, current Editor-in-Chief of Current Allergy and Asthma Reports, and is the newly appointed Secretary-Treasurer of the American Academy of Allergy, Asthma, and Immunology (AAAAI).