Navigating Modern CMV Antivirals: Applying Guideline Updates to Clinical Practice

October 23, 2026

Cytomegalovirus (CMV) remains one of the most common and clinically significant infectious complications following solid organ and allogeneic hematopoietic stem cell transplantation. As recent advances have expanded the therapeutic landscape with newer antiviral agents for CMV prophylaxis and treatment, guideline recommendations have continued to evolve to support optimal CMV prevention, monitoring, and management. Keeping pace with indication expansions, updated guidelines, and emerging clinical data can be challenging, requiring clinicians to reassess how best to integrate evolving evidence into practice across diverse transplant populations. Through case-based discussion, join expert faculty as they examine the evolving roles of newer antiviral therapies, including letermovir and maribavir; review the latest guideline recommendations and emerging clinical data; and discuss their application to real-world transplant scenarios to optimize patient care.

Target Audience

This educational initiative is intended for transplant surgeons, cardiothoracic surgeons/clinicians, infectious disease clinicians, critical care clinicians, hospitalists, nurses, pharmacists, and other HCPs involved in the care of solid organ transplant recipients.

Learning Objectives

Upon completion of this activity, the learner should be able to:

  • Evaluate the clinical data supporting the efficacy and safety of new CMV antivirals across patient populations and post-transplant settings
  • Identify key updates in guideline consensus recommendations for CMV management in solid organ transplant (SOT) and hematopoietic stem cell transplant (HSCT) recipients
  • Develop evidence-based preventative and treatment plans using modern CMV antivirals
  • Assess potential drug-drug interactions with new CMV antivirals to minimize the risk of serious toxicities and adverse effects

Commercial Support
Supported by an educational grant from Takeda Pharmaceuticals U.S.A., Inc.

Course summary

Available credit: 
  • 1.00 ACPE Pharmacist

    Pharmacists
    AKH Inc., Advancing Knowledge in Healthcare designates this continuing education activity for 1.00 contact hours.

  • 1.00 AMA PRA Category 1 Credit™

    Physicians
    AKH Inc., Advancing Knowledge in Healthcare designates this Live Activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 1.00 ANCC Contact Hours

    Nurses
    Credit being awarded: 1.00 ANCC contact hours

  • 1.00 AMA PRA Category 1 Credit™ Non-MD

    Non-Physicians Seeking AMA Credit
    AKH Inc., Advancing Knowledge in Healthcare designates this Live Activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™.

Course opens: 
10/09/2026
Course expires: 
11/23/2026
Event starts: 
10/23/2026 - 6:30pm EDT
Event ends: 
10/23/2026 - 7:30pm EDT
Cost:
$0.00
Add to calendar: 
Rating: 
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Washington, DC 20001
United States

All of the relevant financial relationships listed for these individuals have been mitigated.

Disclosures
It is the policy of AKH Inc. to ensure independence, balance, objectivity, scientific rigor, and integrity in all of its continuing education activities. The author must disclose to the participants any significant relationships with ineligible companies whose products or devices may be mentioned in the activity or with the commercial supporter of this continuing education activity. Identified conflicts of interest are mitigated by AKH prior to accreditation of the activity. AKH planners and reviewers have no relevant financial relationships to disclose.

Disclosure of Unlabeled Use and Investigational Product 
This educational activity may include discussion of uses of agents that are investigational and/or unapproved by the FDA. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer 
This course is designed solely to provide the healthcare professional with information to assist in his/her practice and professional development and is not to be considered a diagnostic tool to replace professional advice or treatment. The course serves as a general guide to the healthcare professional, and therefore, cannot be considered as giving legal, nursing, medical, or other professional advice in specific cases. AKH Inc. specifically disclaim responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through participants misunderstanding of the content. If you would like to opt out from future communications from AKH please send an email to [email protected] with your information with "Opt Out" in the subject line.

Committee Member, Planner, Staff(s)

Dorothy Caputo, MA BSN RN

has no relevant financial relationships to disclose at this time.

Dorothy Duffy, RPh

has no relevant financial relationships to disclose at this time.

Camille Kotton, MD, FIDSA, FAST

has a financial relationship (Consultant) with Takeda QIAGEN Takeda Evrys Biotest Kamada Abbott Labs Roche Diagnostics;.
Reviewer(s)

Dorothy Caputo, MA BSN RN

has no relevant financial relationships to disclose at this time.

Dorothy Duffy, RPh

has no relevant financial relationships to disclose at this time.
Speaker, Instructor, Faculty(s)

Atul Humar, MD, MSc, FRCPC, FAST

has a financial relationship (Consultant) with Takeda;.
has a financial relationship (Speaker) with Kamada;.
has a financial relationship (Speaker) with Takeda;.
has a financial relationship (Speaker) with Eurofins;.
has a financial relationship (Researcher) with Takeda, Synklino;.
has a financial relationship (Consultant) with Merck;.

Camille Kotton, MD, FIDSA, FAST

has a financial relationship (Consultant) with Takeda QIAGEN Takeda Evrys Biotest Kamada Abbott Labs Roche Diagnostics;.

Genovefa Papanicolaou, MD, PhD

has a financial relationship (Speaker) with Taekeda, Merck &Co;.
has a financial relationship (Researcher) with Merck&Co, Aicuris;.
has a financial relationship (Consultant) with Takeda;.
has a financial relationship (Consultant) with Symbio;.
has a financial relationship (Consultant) with Genentech;.
has a financial relationship (Consultant) with Merck &Co;.
has a financial relationship (Consultant) with AiCuris;.

In support of improving patient care, this activity has been planned and implemented by AKH Inc., Advancing Knowledge in Healthcare and Catalyst Medical Education, LLC. AKH Inc., Advancing Knowledge in Healthcare is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

This activity was planned by and for the healthcare team, and learners will receive 1 Interprofessional Continuing Education (IPCE) credit for learning and change.

Available Credit

  • 1.00 ACPE Pharmacist

    Pharmacists
    AKH Inc., Advancing Knowledge in Healthcare designates this continuing education activity for 1.00 contact hours.

  • 1.00 AMA PRA Category 1 Credit™

    Physicians
    AKH Inc., Advancing Knowledge in Healthcare designates this Live Activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 1.00 ANCC Contact Hours

    Nurses
    Credit being awarded: 1.00 ANCC contact hours

  • 1.00 AMA PRA Category 1 Credit™ Non-MD

    Non-Physicians Seeking AMA Credit
    AKH Inc., Advancing Knowledge in Healthcare designates this Live Activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™.

Price

Cost:
$0.00
Please login or register to take this course.

Criteria for Success
Certificates of completion will be awarded based on the participant’s attendance and submission of the activity evaluation/claim credit form. You must participate in the entire activity to receive credit. There is no fee to participate in this activity. If you have questions about this activity, please contact AKH Inc. at [email protected].